全文获取类型
收费全文 | 583317篇 |
免费 | 50653篇 |
国内免费 | 18283篇 |
专业分类
耳鼻咽喉 | 7807篇 |
儿科学 | 10269篇 |
妇产科学 | 9384篇 |
基础医学 | 72527篇 |
口腔科学 | 16197篇 |
临床医学 | 47583篇 |
内科学 | 69217篇 |
皮肤病学 | 8943篇 |
神经病学 | 30336篇 |
特种医学 | 18683篇 |
外国民族医学 | 222篇 |
外科学 | 55871篇 |
综合类 | 92219篇 |
现状与发展 | 87篇 |
一般理论 | 29篇 |
预防医学 | 45690篇 |
眼科学 | 7596篇 |
药学 | 57865篇 |
414篇 | |
中国医学 | 41863篇 |
肿瘤学 | 59451篇 |
出版年
2024年 | 594篇 |
2023年 | 8637篇 |
2022年 | 12657篇 |
2021年 | 22595篇 |
2020年 | 21829篇 |
2019年 | 22549篇 |
2018年 | 21719篇 |
2017年 | 21559篇 |
2016年 | 21337篇 |
2015年 | 21691篇 |
2014年 | 33832篇 |
2013年 | 38385篇 |
2012年 | 33475篇 |
2011年 | 37475篇 |
2010年 | 28889篇 |
2009年 | 27130篇 |
2008年 | 28402篇 |
2007年 | 29897篇 |
2006年 | 27224篇 |
2005年 | 24381篇 |
2004年 | 20693篇 |
2003年 | 18229篇 |
2002年 | 14570篇 |
2001年 | 12982篇 |
2000年 | 10914篇 |
1999年 | 9108篇 |
1998年 | 7174篇 |
1997年 | 6875篇 |
1996年 | 6058篇 |
1995年 | 6000篇 |
1994年 | 5482篇 |
1993年 | 4505篇 |
1992年 | 4017篇 |
1991年 | 3718篇 |
1990年 | 3078篇 |
1989年 | 2747篇 |
1988年 | 2606篇 |
1987年 | 2258篇 |
1986年 | 2076篇 |
1985年 | 3824篇 |
1984年 | 3744篇 |
1983年 | 2530篇 |
1982年 | 2974篇 |
1981年 | 2248篇 |
1980年 | 1989篇 |
1979年 | 1672篇 |
1978年 | 1251篇 |
1977年 | 958篇 |
1976年 | 1059篇 |
1975年 | 701篇 |
排序方式: 共有10000条查询结果,搜索用时 156 毫秒
101.
102.
103.
104.
Derek K. Chu Romina Brignardello-Petersen Gordon H. Guyatt Cristian Ricci Jon Genuneit 《Pediatric allergy and immunology》2022,33(1):e13609
Network meta-analyses (NMAs) simultaneously estimate the effects of multiple possible treatment options for a given clinical presentation. For allergists to benefit optimally from NMAs, they must understand the process and be able to interpret the results. Through a worked example published in Pediatric Allergy and Immunology, we summarize how to identify credible NMAs and interpret them with a focus on recent innovations in the GRADE approach (Grading of Recommendations Assessment, Development, and Evaluation). NMAs build on traditional systematic reviews and meta-analyses that consider only direct paired comparisons by including indirect evidence, thus allowing the simultaneous assessment of the relative effect of all pairs of competing alternatives. Our framework informs clinicians of how to identify credible NMAs and address the certainty of the evidence. Trustworthy NMAs fill a critical gap in providing key inferences using direct and indirect evidence to inform clinical decision making when faced with more than two competing courses of treatment options. This document will help allergists to identify trustworthy NMAs to enhance patient care. 相似文献
105.
《Journal d'obstetrique et gynecologie du Canada》2022,44(10):1054-1060
ObjectiveTo determine the baseline and cumulative risks of cervical intraepithelial lesion grade 3 (CIN3) and invasive cervical cancer in patients with <CIN2 colposcopy findings after a low-grade screening cytology finding (atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion [LSIL]).MethodsBy linking administrative databases, including cytology, pathology, cancer registries, and physician billing history, a population-based cohort study was performed on participants with <CIN2 initial colposcopy results after a low-grade antecedent cytology finding, between January 2012 and December 2013. Three and 5-year risks of CIN3 and invasive cervical cancer were generated using Kaplan-Meier survival analysis.ResultsAmong the 36 887 participants included in the study, CIN3 incidence based on referral cytology were as follows at 3 and 5 years, respectively: normal, 0.7% and 0.9%; ASCUS, 4.31% and 5.6%; and LSIL, 5.9% and 7.2%. Three- and 5-year incidence of invasive cancer were 0% and 0.02% for normal cytology, 0.08% and 0.11% for ASCUS, and 0.04% and 0.07% for LSIL, respectively. Stratifying risk by biopsy result at initial colposcopy, 3- and 5-year CIN3 incidences were 2.85% and 3.81% with a negative biopsy, 7.09% and 8.32% with an LSIL biopsy, and 4.11% and 5.2% when no biopsy was done, respectively. Three- and 5-year incidence of invasive cancer was 0% and 0.05% after a negative biopsy, 0% and 0% after LSIL biopsy, and 0.05% and 0.08% when no biopsy was done, respectively.ConclusionWhen initial colposcopy is done after a low-grade screening cytology result and <CIN2 is identified, the risk of CIN3 and invasive cancer is low, particularly when biopsies indicate LSIL. Surveillance strategies should balance the likelihood of detecting CIN3 with the potential harms over management with too frequent screening or colposcopic interventions in low-risk patients. 相似文献
106.
《Mayo Clinic proceedings. Mayo Clinic》2022,97(7):1282-1293
ObjectiveTo assess the association between adherence to a Mediterranean lifestyle and changes in pain, and its characteristics over time in older adults.Patients and MethodsWe analyzed data from 864 and 862 community-dwelling individuals aged 65+ years from the Study on Cardiovascular Health, Nutrition and Frailty in Older Adults in Spain (Seniors-ENRICA) Seniors-ENRICA-1 (2008–2010 to 2012) and Seniors-ENRICA-2 (2015–2017 to 2019) cohorts, with a median follow-up of 2.8 and 2.4 years, respectively. Adherence to a Mediterranean lifestyle was assessed at baseline with the 27-item Mediterranean lifestyle (MEDLIFE) index. Pain changes over time were calculated with a pain scale that assessed the frequency, severity, and the number of pain locations both at baseline and follow-up. Multivariable-adjusted relative risk ratios (RRRs) were obtained using multinomial logistic regression.ResultsIn the pooled cohorts, after a median follow-up of 2.6 years, pain worsened for 697 participants, improved for 734, and did not change for 295. Compared with the lowest category of MEDLIFE adherence, those in the highest category showed an RRR of improvement vs worsening of overall pain of 1.85 (95% CI, 1.28 to 2.67; P-trend<.001). MEDLIFE adherence was also linked to improvement in pain frequency (RRR, 1.98; 95% CI, 1.31 to 3.01; P-trend=.001), pain severity (RRR, 2.00; 95% CI, 1.33 to 3.00; P-trend=.001), and a reduction in the number of pain locations (RRR, 1.68; 95% CI, 1.13 to 2.50; P-trend=.004). Limitations of this study are the use of self-reported lifestyle data.ConclusionA Mediterranean lifestyle was associated with improvement of pain characteristics in older adults. Experimental studies should assess the efficacy of an integral lifestyle approach for the management of pain in older adults. 相似文献
107.
108.
背景 随着患者就诊下沉明显,联合家庭医生团队开展社区药学服务日益重要,但如何发挥家庭医生团队作用以满足患者社区药学服务需求仍有待进一步探索。 目的 了解上海市社区药学服务需求现状,为改进社区药学人员参与家庭医生团队开展服务的方式提供参考建议。 方法 于2020年9—12月,采用多阶段抽样法抽取349例老年慢性病患者和855例家庭医生团队主要成员〔全科医生(n=481)、护士(n=234)、公共卫生医生(n=140)〕进行问卷调查。针对老年慢性病患者的调查问卷主要内容包括基本情况、患病情况、用药情况、社区药学服务需求情况和社区药学服务利用情况。针对家庭医生团队成员的调查问卷主要内容包括基本情况、社区药学服务认知情况和社区药学服务需求情况。 结果 349例老年慢性病患者中,125例(35.8%)同时患有≥3种慢性病,305例(87.4%)每日需多次用药。用药管理类药学服务方面,"用药重整及随访"需求人数最多,为52例(14.9%),"用药随访"利用人数最多,为49例(14.0%)。用药教育类药学服务方面,"慢性病用药特殊性的普及教育"需求人数最多,为247例(70.8%),"宣传健康生活方式"利用人数最多,为33例(9.4%)。家庭医生团队成员中,全科医生、护士、公共卫生医生对药学服务的了解程度方面,分别有440例(91.5%)、202例(86.3%)、112例(80.0%)表示了解;对药师的信任程度方面,分别有302例(62.8%)、183例(78.2%)、103例(73.6%)表示非常信任;"协同医师做好药物使用遴选"服务项目的需求人数分别有359例(74.6%)、112例(47.9%)、81例(57.8%);"指导护士使用与管理药品"服务项目的需求人数分别有190例(39.5%)、153例(65.4%)、57例(40.7%)。 结论 一方面患者实际迫切需要用药管理类药学服务,另一方面患者的用药教育类药学服务需求远未得到满足。鉴于社区药学人员队伍薄弱及家庭医生团队对社区药学服务认知局限的现状,社区药学人员应通过培训团队成员,提升团队的社区药学服务认知水平及服务能力,借助团队力量及成员特性,更广泛高效地开展社区药学服务。 相似文献
109.
朱丹 《临床超声医学杂志》2022,24(9)
冻结肩是常见的肩部疾病,传统非可视化治疗冻结肩效果欠佳。近年来,超声引导具有动态实时定位、无辐射、便携性、低成本等优点在辅助诊断和治疗冻结肩患者中得到成功应用,不仅能提供精确的诊断,也提高了患者中长期的疗效。本文就超声引导辅助诊断和治疗冻结肩的研究进展进行综述。 相似文献
110.